Wednesday, July 23, 2008

Endometrial Biopsy

I'm going in to have a biopsy done tomorrow. Some studies show that women who have failed IVFs sometimes have success after having a biopsy done. I guess the biopsy process "changes" the lining of your uterus.

I'm just anticipating pain. My HSG was very painful. I realize that it's not the same, but it still seems painful.

Why else do they do an endometrial biopsy?
They might find abnormal cells.
You may have problems with your lining.
Your hormone levels might be off.
You might have an infection you didn't know about.
Your RE might suspetct endohyperplasia (related to low estrogen and low progesterone.)

Basically - if you have a problem with any of these things, you might have a problem supporting a pregnancy.

Oh, I also tested + for MTHFR - Methylenetetrahydrofolate reductase. It's a gene mutation which can in some cases lead to problems getting or staying pregnant. In my case, I'm not absorbing/processing folic acid and they are putting me on Folgard. I'm not sure which mutation I have - I guess there's two. One of them can lead to blood clotting issues.


Amy said...


My HSG was also VERY painful, but the endometrial biopsy was painless...just felt a small pinch and that was it. Hoping your experience is the same!

Good luck!


Wendy said...

Oh, that's good to hear that it was okay for you. I am really hoping it's not a big deal today.

Misty River said...


This all sounds very positive to me! I hope you feel a little more comfort with the knowledge of the mutation you tested positive for.

I wish you only more answers with the biopsy and I hope there isn't much pain.

Good luck with #3!! Hopefully, third time will be the charm for you!!

Pria said...

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